D'Andrea Lab News
Alan D’Andrea, MD elected to National Academy of Sciences
Open Positions at the D'Andrea Lab
1. Research Technician
2. Summer Internships
News Releases 2002
1. By Blocking DNA Repair, Drug Combination Proves Lethal to Hard-to-Treat Tumor Cells
2. Dana-Farber Cancer Institute Receives $11 M to Intercept and Cure Deadly Cancers
3. How Science, Collaboration and Persistence Fueled a Promising New Drug Combination for Ovarian Cancer
4. Dana-Farber Researchers Devise Powerful New Drug Pairings to Improve the Effectiveness of Ovarian Cancer Therapies
1. By Blocking DNA Repair, Drug Combination Proves Lethal to Hard-to-Treat Tumor Cells
2. Dana-Farber Cancer Institute Receives $11 M to Intercept and Cure Deadly Cancers
3. How Science, Collaboration and Persistence Fueled a Promising New Drug Combination for Ovarian Cancer
4. Dana-Farber Researchers Devise Powerful New Drug Pairings to Improve the Effectiveness of Ovarian Cancer Therapies
New Publications
August 2022
1. Li F, Sarangi P, Iyer DR, Feng H, Moreau L, Nguyen H, Clairmont C, D'Andrea AD. CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair. Cell Rep. 2022 Aug 30;40(9):111297. doi: 10.1016/j.celrep.2022.111297. PMID: 36044844.
2.Patterson-Fortin J, Bose A, Tsai WC, Grochala CJ, Nguyen H, Zhou J, Parmar K, Lazaro JB, Liu JF, McQueen K, Shapiro GI, Kozono D, D'Andrea AD. Targeting DNA repair with combined inhibition of NHEJ and MMEJ induces synthetic lethality in TP53-mutant cancers. Cancer Res. 2022 Aug 16:CAN-22-1124. doi: 10.1158/0008-5472.CAN-22-1124. Epub ahead of print. PMID: 35972384.
October 2022
1. da Costa, A.A.B.A., Chowdhury, D., Shapiro, G.I. et al. Targeting replication stress in cancer therapy. Nat Rev Drug Discov (2022). https://doi.org/10.1038/s41573-022-00558-5
November 2022
1. Iyer DR, Harada N, Clairmont C, Jiang L, Martignetti D, Nguyen H, He YJ, Chowdhury D, D'Andrea AD. CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2214935119. doi: 10.1073/pnas.2214935119. Epub 2022 Nov 29. PMID: 36442094.
March 2023
1. Patterson-Fortin, J., Jadhav, H., Pantelidou, C. et al. Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer. Nat Commun 14, 1390 (2023). https://doi.org/10.1038/s41467-023-37096-6
1. Li F, Sarangi P, Iyer DR, Feng H, Moreau L, Nguyen H, Clairmont C, D'Andrea AD. CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair. Cell Rep. 2022 Aug 30;40(9):111297. doi: 10.1016/j.celrep.2022.111297. PMID: 36044844.
2.Patterson-Fortin J, Bose A, Tsai WC, Grochala CJ, Nguyen H, Zhou J, Parmar K, Lazaro JB, Liu JF, McQueen K, Shapiro GI, Kozono D, D'Andrea AD. Targeting DNA repair with combined inhibition of NHEJ and MMEJ induces synthetic lethality in TP53-mutant cancers. Cancer Res. 2022 Aug 16:CAN-22-1124. doi: 10.1158/0008-5472.CAN-22-1124. Epub ahead of print. PMID: 35972384.
October 2022
1. da Costa, A.A.B.A., Chowdhury, D., Shapiro, G.I. et al. Targeting replication stress in cancer therapy. Nat Rev Drug Discov (2022). https://doi.org/10.1038/s41573-022-00558-5
November 2022
1. Iyer DR, Harada N, Clairmont C, Jiang L, Martignetti D, Nguyen H, He YJ, Chowdhury D, D'Andrea AD. CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2214935119. doi: 10.1073/pnas.2214935119. Epub 2022 Nov 29. PMID: 36442094.
March 2023
1. Patterson-Fortin, J., Jadhav, H., Pantelidou, C. et al. Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer. Nat Commun 14, 1390 (2023). https://doi.org/10.1038/s41467-023-37096-6
New Members
June 2022
D'Andrea Lab welcomes Noella Holmer our new Research Technician .
November 2022
Welcome Yuna Hirohashi ! Our new Senior Research Technician.
February 2023
Welcome Ozge Somuncu! Our new Senior Scientist and Organoid Core Director!
March 2023
Welcome Guang-Li Zhu ! New Postdoctoral Fellow in the D'Andrea lab.
D'Andrea Lab welcomes Noella Holmer our new Research Technician .
November 2022
Welcome Yuna Hirohashi ! Our new Senior Research Technician.
February 2023
Welcome Ozge Somuncu! Our new Senior Scientist and Organoid Core Director!
March 2023
Welcome Guang-Li Zhu ! New Postdoctoral Fellow in the D'Andrea lab.
