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        Selected Publications (from over 200 peer-reviewed publications) 
  1. Kupfer GM, Naf D, Suliman A, Pulsipher M, D’Andrea AD.  The Fanconi anaemia proteins, FAA and FAC, interact to form a nuclear complex.  Nature Genetics 17:487-490, 1997.
  2. Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C. Hejna J, Grompe M, D’Andrea AD.   Interaction of the Fanconi Anemia Proteins and BRCA1 in a common pathway.   Molecular Cell 7:249-262, 2001.
  3. Taniguchi T, Garcia-Higuera I, Xu B, Andreassen P, Gregory RC, Lane WS, Kim S-T, Kastan MB, D’Andrea AD.  Convergence of the Fanconi Anemia and Ataxia Telangiectasia signaling pathways.  Cell 109:459-472, 2002.
  4. Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, de Die-Smulders C, Persky N, Grompe M, Joenje H, Pals G, Ikeda H, Fox EA, D’Andrea AD. Biallelic inactivation of BRCA2 in Fanconi Anemia.  Science 297:606-609, 2002.
  5. Taniguchi T, Tischkowitz M, Ameziane N, Hodgson SV, Mathew CG, Joenje H, Mok SC, D’Andrea AD.  Disruption of the Fanconi Anemia/BRCA pathway in cisplatin-sensitive ovarian tumors.  Nature Medicine 9:568-74, 2003
  6. Cohn MA, Kowal P, Yang K, Haas W, Huang T, Gygi SP, D’Andrea AD.  A UAF1-containing multisubunit protein complex regulates the Fanconi Anemia Pathway. MolCell 28:786-797, 2007.
  7. Kee Y, Kim JM, D’Andrea AD.  Regulated Degradation of FANCM in the Fanconi Anemia Pathway during Mitosis. 2009 Genes and Devel. 1:23(5):555-60. PMCID: PMC2658523
  8. D'Andrea AD. Susceptibility pathways in Fanconi's anemia and breast cancer. 2010 N Engl J Med 362: 1909-1919. PMC3069698
  9. Huang M, Kim JM, Shiotani B, Yang K, Zou L, D’Andrea AD.  The FANCM/FAAP24 Complex is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response.  2010 Mol Cell. 39(2):259-68. PMC2928996
  10. Yang K, Moldovan GL, Vinciguerra P, Murai J, Takeda S, D'Andrea AD. Regulation of the Fanconi anemia pathway by a SUMO-like delivery network. Genes Dev. 2011 Sep 1;25(17):1847-58. PMC3175720
  11. Moldovan GL, Dejsuphong D, Petalcorin M, Hofmann K, Takeda S, Boulton S, D’Andrea AD.  Inhibition of homologous recombination by the PCNA-interacting protein PARI.  2012 Molecular Cell 45: 75-86 PMC3267324
  12. Kim H, Yang K, Dejsuphong D, D’Andrea, AD. Regulation of Rev1 by the Fanconi Anemia Core Complex. Nat Struct Mol Biol. 2012 Jan 22;19(2):164-70. PMC3280818
  13. Park E, Kim H, Kim JM, Primack B, Vidal-Cardenas S, Xu Y, Price BD, Mills AA, D’Andrea AD.  FANCD2 Activates Transcription of TAp63 and Suppresses Tumorigenesis. Mol Cell. 2013 Jun 27;50(6):908-18. 
  14. Price BD, D'Andrea AD. Chromatin remodeling at DNA double-strand breaks. Cell. 2013 Mar 14;152(6):1344-54. PMC3670600
  15. Ceccaldi R, Liu J, Amunugama R, Hajdu I, Primack B, Petalcorin MIR, O’Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D’Andrea AD. Homologous recombination (HR)-deficient tumors are hyper-dependent on POLQ-mediated repair. Nature. 2015 Feb 12;518(7538):258-62.
  16. Hill SJ, Decker B, Roberts EA, Horowitz NS, Muto MG, Worley MJ Jr, Feltmate CM, Nucci MR, Swisher EM, Nguyen H, Yang C, Morizane R, Kochupurakkal BS, Do KT, Konstantinopoulos PA, Liu JF, Bonventre JV, Matulonis UA, Shapiro GI, Berkowitz RS, Crum CP, D'Andrea AD. Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids. Cancer Discov. 2018 Nov;8(11):1404-1421.
  17. Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, Parmar K, Yusufzai T, Zheng N, D'Andrea AD. USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors. Mol Cell. 2018 Dec 20;72(6):925-941.
  18. Clairmont CS, Sarangi P, Ponnienselvan K, Galli LD, Csete I, Moreau L, Adelmant G, Chowdhury D, Marto JA, D'Andrea AD. TRIP13 regulates DNA repair pathway choice through REV7 conformational change. Nat Cell Biol. 2020 Jan;22(1):87-96. 
  19. Zhou J, Gelot C, Pantelidou C, Li A, Yücel H, Davis RE, Färkkilä A, Kochupurakkal B, Syed A, Shapiro GI, Tainer JA, Blagg BSJ, Ceccaldi R, D'Andrea AD. A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors. Nat Cancer. 2021 Jun;2(6):598-610.


       Selected Reviews

  1. Kim H, D’Andrea AD. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev. 2012 Jul 1;26(13):1393-408.
  2. Kee, Y, D’Andrea, AD. Molecular Pathogenesis and Clinical Management of Fanconi Anemia, Journal of Clinical Investigation, J Clin Invest. 2012 Nov 1;122(11):3799-806. 
  3. Kee Y, D'Andrea AD. Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev. 2010 Aug 15;24(16):1680-94.
  4. Moldovan, G. L. & D'Andrea, A. D. How the Fanconi anemia pathway guards the genome. Annu Rev Genet 43, 223-249 (2009). PMCID: PMC2830711
  5. ​Clairmont CS, D'Andrea AD. REV7 directs DNA repair pathway choice. Trends Cell Biol. 2021 Dec;31(12):965-978.